HPLC and Liquid Chromatography Products

Solvent Filtration and Degassing Products

LAZAR INTRODUCES...
Pure and Simple Solutions to Liquid Chromatography Problems.
HPLC, as an analytical tool for detection and separation of chemical
compounds,
has become the most important laboratory technique over the last decade. As
with all analytical techniques, minor processing problems sometimes appear
which in the long run can have major impact on the accuracy of the system as
well as its durability.
Although the evolution of liquid chromatographs has brought the instruments
via the microprocessor into the computer age there are still problems which
the computer cannot solve.
This is why we at LAZAR have spent the majority of our R & D time in solving
those seemingly simple but persistent problems so that we can proudly tell
you that we have the pure and simple chromatography solutions.

VERSATILITY AND FLEXIBILITY
The LAZAR Filter-Degasser can be used to accommodate almost all HPLC
applications. For most ISOCRATIC applications, the Filter-Degasser can be
directly screwed onto the popular 1 liter HPLC solvent/reservoir bottle (38mm
cap). In this fashion, it is not necessary to further transfer the filtered-
degassed solvent where reabsorption of gasses as well as particle
contamination
can further occur. 28mm and 33mm caps for 250 and 500 ml bottles are also
available.
The Filter-Degasser with 38mm cap also fits on the standard one gallon (4
liter)
solvent bottle for filtration and degassing of solvent without requiring an
operator's attention. A gallon of solvent can usually be filtered in less than
10 minutes. Further, the Filter-Degasser is also available with 24/40 and
19/22
standard taper for use with various Erlenmeyer and volumetric flasks. In
addition it can be used with a 40/35 standard taper for use with the
Millipore® type filtration flasks.
For most GRADIENT separations, binary or ternary, LAZAR offers a versatile
manifold system where simultaneous vacuum filtration and degassing of 2 or 3
solvents can be run from one vacuum source.
The manifold system features individual shutoff valves for each vacuum
operation, quick disconnect couplings for the individual filtration units,
a master control valve for adjusting vacuum flow, and a disposable vacuum
line filter as a safety feature against pump contaminants.  The manifold
can be attached to any vacuum source.


 All fluoropolymer Filter Degasser

 Chempure All PFA fluoropolymer Filteration System 




ALL FLUOROPOLYMER FILTER-DEGASSER -the Simple Approach
to Solvent Purification
  
Features
*All PFA fluoropolymer construction- inert to most solvents, aqueous
or organic.
*Simple to install- fits directly on your standard solvent bottles or
 Erlenmeyer flasks.
*Simple and economical to use- attach to any available vacuum line,
put in
 the filter and you're operational.
*In-line device can filter/degass 1 gallon in less than 10 minutes.
*Vacuum line also establishes siphon to transfer solvent to storage
bottle.

Filtration and degassing of solvents and samples prior to analysis is
recommended by most instrument manufacturers. Instrument manufacturers
understand that particulate matter in solvents can cause damage to expensive
pumps, clog analytical columns, and in general cause wear and tear to the
instruments.
The combination of particulate matter and dissolved gasses in solvents can
also create spurious peaks or can result in baseline instability. Dissolved
oxygen in solvents can cause direct interference with fluorescence and
electrochemical detectors. HPLC grade solvents, even though filtered prior to
shipment by the manufacturer, can accumulate particles during storage due to
shedding from the solvent containers and solvent condensation or
polymerization. The use of salts and buffers can also significantly
contribute to particles in the mobile phase.
Filtration and degassing of solvents with the LAZAR Filter/Degasser reduces
instrument down-time, prolongs the life of the analytical columns, pumps,
and valves and most importantly helps the instrument perform in optimal
fashion.

Ordering Information

ITEM				  CATALOG NO.	   DESCRIPTION
Filter Degasser			   FG-256	    with 38 mm cap.
      "				   FG-256-33	    with 33 mm cap.
      "				   FG-256-28	    with 28 mm cap.
      "				   FG-256-24	    with 24/40 std. taper.
      "				   FG-256-22	    with 19/22 std. taper.
      "				   FG-256-35	    with 40/35 std. taper.

Filter Membranes		   SM-256	    fluoropolymer filter membranes
(47 mm dia., 0.2 micro-				    for organic solvents,
meter porosity)					    pkg. of 10.

Filter Membranes		   SM-256A          Hydrophillic filter
(47 mm dia., 0.45 micro-			    membranes for
meter porosity)					    aqueous solvents,
						    pkg. of 10


Return Top of Page
Get Additional Information on Product
How to Order


CHEMPURE ALL PFA fluoropolymer FILTRATION SYSTEM
  
HIGH PURITY PREPARATION OF SOLVENTS AND SAMPLES.

Features
*All PFA fluoropolymer construction for chemical inertness.
*Versatility and flexibility with adapters to accommodate most solvent
 bottles and Erlenmeyer flasks.
*All PFA fluoropolymer funnel-volume 150 ml is standard with 300 ml
optional.
*PFA fluoropolymer screen to hold filter membranes.
*Costs significantly lower than all competitive units.

For the ultimate in filtration and degassing of discreet samples and specific
volumes of solvents, LAZAR presents the Chempure Filtration System. Compared
to the Filter-Degasser which is an "in-line" processing units, the Chempure
is ideal for use where specific volumes of sample and/or solvent must be
filtered and degassed.
As with the LAZAR Filter-Degasser, the Chempure system offers maximum
flexibility being available with various adapter caps for direct use with
1 liter solvent reservoir bottles, 1 gallon solvent bottles, Erlenmeyer flasks
in the range of 125 to 1000 ml which have the 24/40 glass joint or the 40/35
glass joint Millipore®  type flask. Chempure funnel volume is 150 ml and this
can be increased to 300 ml with the use of an all fluoropolymer funnel
extender. The
Chempure system is useable with most organic and aqueous solvents and samples.


Ordering Information

ITEM				  CATALOG NO.	   DESCRIPTION
Chempure Filtration System	   CP-256	    with 38 mm cap.
	  "    		           CP-256-33	    with 33 mm cap.
	  "			   CP-256-28	    with 28 mm cap.
	  "			   CP-256-24	    with 24/40 std. taper.
	  "		           CP-256-22	    with 19/22 std. taper.
	  "			   CP-256-35	    with 40/35 std. taper.
	  "			   A-256	     fluoropolymer funnel extender

Filter Membranes		   SM-256C	    fluoropolymer Filter mem-
(47 mm dia., 0.2 micrometer			    branes for organic sol-
porosity)					    vents, pkg of 10.

Filter Membranes		   SM-256CA	    Hydrophillic filter mem-
(47 mm dia., 0.45 micrometer			    branes for aqueous sol-
porosity)					    vents, pkg of 10.

Vacuum Filtration Manifold System  VFM-266	    with 3 Filter-Degassers
	     "		           VFM-266C	    with 3 chempures
	     "		           VFM-266N	    without filtration units


Return Top of Page
Get Additional Information on Product
How to Order




Solvent Storage Systems and Dispensing Accessories



 Solvent Bottle Cap Assemblies 
 Total Systems Concept for Isocratic and Gradient Requirments



SOLVENT BOTTLE CAP ASSEMBLIES

Open solvent reservoir bottles or bottles with makeshift caps can lead to
particle contamination and absorption of gasses during the storage and
dispensing of solvent which has previously been filtered and degassed.
LAZAR offers two unique bottle cap assemblies which can minimize solvent
recontamination and gas absorption. These assemblies fit the standard 1 liter
solvent bottle (38mm caps) or 500 and 250ml bottle (28 and 33mm caps).
Adapter cap assemblies are also available for Erlenmeyer flasks with 24/40
standard taper. For users of the Millipore®  type glass filtration apparatus,
LAZAR offers a filter reservoir cap (40/35 standard taper) which fits directly
onto the Millipore® type filtration flasks. This flask now becomes the solvent
reservoir eliminating solvent repouring and the risk of recontamination and
aeration.


 Filter Reservoir Caps (FRC)
 Dispenser Reservoir Caps (DRC)
 LAZAR fluoropolymer Solvent Reservoir (TSR)




FILTER RESERVOIR CAP (FRC)
  
The FRC is a solvent reservoir cap with 1/8 PFA fluoropolymer tubing which
attaches
directly onto the HPLC pump. An air vent with disposable membrane filter for
minimizing air contamination and solvent evaporation is included.

ORDERING INFORMATION

ITEM				    CATALOG NO.		DESCRIPTION

Filter Reservoir Cap		      FRC-1		cap, 38mm.
	"			      FRC-2		cap, 33mm.
	"			      FRC-3		cap, 28mm.
	"			      FRC-4		cap, 24/40 std. taper.
	"			      FRC-5		cap, 40/35 std. taper.



DISPENSER RESERVOIR CAP (DRC)
The second type cap assembly available,  the Dispenser Reservoir Cap (DRC),
also minimizes solvent contamination by permitting direct transfer of solvent
via a vacuum siphon without repouring or air exposure. An on/off switching
valve on the cap assembly allows the pump to be turned off during vacuum
transfer. The use of vacuum minimizes reabsorption of atmospheric gasses.

ORDERING INFORMATION

ITEM				    CATALOG NO.		DESCRIPTION
Dispenser Reservoir Cap		      DRC-1		cap, 38mm.
	"			      DRC-2		cap, 33mm.
	"			      DRC-3		cap, 28mm.
	"			      DRC-4		cap, 24/40 std. taper.
	"			      DRC-5		cap, 40/35 std. taper


LAZAR fluoropolymer SOLVENT RESERVOIR (TSR)
With a total concern for laboratory safety as well as avoidance of possible
contamination problems, LAZAR presents our innovative all PFA fluoropolymer
Solvent
reservoir bottle. Manufactured from thick walled PFA fluoropolymer, the TSR
eliminates the
possibility of implosions during a vacuum process.
The total inertness of PFA fluoropolymer to almost all organic solvents as
well as
aqueous solvents eliminates contamination problems such as alkali leaching
from glass and subsequent pH change in solvents. As a final benefit of the
TSR, the thick, opaque walls of the reservoir protect photosensitive solvents
from the effects of extraneous radiation. As with the solvent bottle cap
above, the fluoropolymer Solvent bottles come with either a filtered air
vent or
PFA fluoropolymer resin siphon for vacuum solvent transfer directly to the
solvent bottle.

ORDERING INFORMATION

ITEM				    CATALOG NO.		DESCRIPTION
fluoropolymer Solvent Reservoir
    with air vent		      TSV-1		1 liter
	"			      TSV-2		500ml.
	"			      TSV-3		250ml.
fluoropolymer Solvent Reservoir
    with siphon			      TSS-1		1 liter
	"			      TSS-2		500ml.
	"			      TSS-3		250ml.


Return Top of Page
Get Additional Information on Product
How to Order




TOTAL SYSTEMS CONCEPT FOR ISOCRATIC AND GRADIENT REQUIREMENTS
   
For the HPLC user who wants the ultimate in convenience, simplicity,
contaminant free and degassed solvents, LAZAR offers the all PFA fluoropolymer Solvent
Reservoir Systems for isocratic, binary, and ternary work. For ISOCRATIC work,
a Filter-Degasser unit is mounted on top of the 0.25, 0.50, or 1 liter size
fluoropolymer solvent bottle. The solvent is simutaneously filtered and
degassed as
it enters the fluoropolymer bottle. The solvent is stored in the
fluoropolymer reservoir and
is delivered to the pump via 1/8 TFE tubing with ¼-28 end fittings.
Particle contamination and reabsorption of environmental gasses is minimized
due to the complete closure of the system. The above system can be fitted with
a Chempure filtration unit to achieve the same results with discrete solvent
volumes. For the HPLC user who is doing binary or ternary GRADIENT work,
LAZAR offers the total solvent reservoir system. This system consists of 2
or 3 fluoropolymer solvent bottles, retrofitted with Filter-Degassers,
and a system
console featuring a selector switch for the simultaneous filtering, degassing,
and filling of any of the individual solvent reservoirs. This selector switch
allows vacuum to be activated to the appropriate solvent bottle as the dip
tube is dipped into fresh solvent. After the filling operation is complete, a
second lever is pulled relieving vacuum and applying an inert helium blanket
to the solvent bottle. This system offers the ultimate in purification and
dispensing of multiple solvents while offering the user a pure and simple way
to handle solvents.
The front panel of the system console also provides three ¼-28 standard
receptacles for plumbling directly to the HPLC pump.  The system console can
be purchased separately for use with glass or other types of solvent bottles.

ORDERING INFORMATION
ITEM			       CATALOG NO.	  DESCRIPTION

Fluoropolymer Reservoir Isocratic	S-286		   1 liter with Filter-Degasser
	  "			S-286-50	   500ml with Filter-Degasser
	  "			S-286-25	   250ml with Filter-Degasser
	  "   			S-286CP		   1 liter with Chempure Filter
	  "			S-286CP-50	   500ml with Chempure Filter
	  "			S-286CP-25	   250ml with Chempure Filter

fluoropolymer Reservoir System         SB-286	      2 one liter
fluoropolymer bottles with
	binary				    filter-Degassers and system console
	  "			SB-286CP      2 one liter fluoropolymer bottles with
					    Chempure funnels and system console

fluoropolymer Reservoir System 	ST-286	      3 one liter fluoropolymer bottles with             ternary				    Filter-Degassers and system console
	  "			ST-286CP      3 one liter fluoropolymer bottles with Chem-
					    pure funnels and system console.

System Console		        SC-286	      System console without fluoropolymer
					      bottles.

Return Top of Page
Get Additional Information on Product
How to Order




THE TOTALLY PULSELESS LIQUID PUMP

 
YOU CAN NOW DO LC WITH ZERO BASELINE DRIFT GREAT FOR HPLC POST COLUMN
DERIVITIZATION AND FIA


Features
*TOTALLY PULSELESS LIQUID DELIVERY. Unlike single or dual piston
LC/HLPC
 pumps, this revolutionary gas driven pump offers totally pulseless solvent
 or mobile phase delivery. A piston pump with even the best pulse dampener
 cannot offer totally pulseless delivery.

*MINIMIZE BASELINE DRIFT AND IMPROVE LC PERFORMANCE. This pulseless
pump
 totally eliminates baseline drift caused by pressure fluctuations at the pump
 head and thereby greatly improves overall LC performance.

*OPTIMIZE HPLC POSTCOLUMN DERIVITIZATION. The Zero-Pulse pump is
ideal for
 post column derivitization in HPLC where a steady flow of derivitization
 reagent is required.

*WIDE FLOW RANGE. The Zero-Pulse pump can be adjusted to give flow
rates
 from 5 microliters/min. to 30 ml/min.

*COMPATIBLE WITH MOST AQUEOUS AND ORGANIC SOLVENTS. All pump components
 making contact with the solvent are polypropylene and 
fluoropolymer for the low
 pressure pump and 316 stainless steel and fluoropolymer for the medium pressure
 pump. A fluoropolymer liner  is also available for exposure
of Solvents to fluoropolymer
 only.

*COMPATIBLE WITH STANDARD LC/HPLC PLUMBING. The Zero-Pulse pump uses
 standard ¼-28 plastic fittings which are compatible with all LC/HPLC systems.

APPLICATION AREAS
*Low/Medium Pressure LC
*HPLC Postcolumn derivitization
*Flash Chromatography-organic synthesis
*RNA/DNA Synthesis
*Critical Reagent Feeding
*FIA

ORDERING INFORMATION
Low pressure Pump (0 to 70 psi). Includes thick walled polypropylene liquid
reservoir,  fluoropolymer plumbing and fittings pressure gauge
and regulator (use
with helium or nitrogen pressure source).
	0.5 liter pulseless pump			LPP-296ZP
	1.0 liter pulseless pump			LPP-297ZP
	2.0 liter pulseless pump			LPP-298ZP

Medium Pressure Pump (0 to 100 psi). Includes Stainless steel liquid
reservoir,
fluoropolymer plumbing and fittings, pressure gauge and regulator
(use with helium or
nitrogen pressure source).
	10 liter pulseless pump			LPP-299ZP
	20 liter pulseless pump			LPP-300ZP

Return Top of Page
Get Additional Information on Product
How to Order




Low Cost HPLC Column Temperature Control
  
HPLC water jacket is most effective yet lowest cost method for column
temperature control.  Fits most analytical and prep columns.

Ordering Information
model WJ-276A for HPLC columns 3 to 30cm long.
model WJ-276B for HPLC columns 30 to 50cm long.
model WJ-276C for HPLC columns 50 to 100cm long.

Return Top of Page
Get Additional Information on Product
How to Order